Upton over the years has had three Parish Churches, each one in a different location and each with its own burial ground. The first parish church was the Norman Church, which stood by Moreton Road. The second was the Greenbank Church, which stood on Greasby Road and the third is St Mary's, the current parish church which stands on Ford Road. It is possible that there was a Saxon Church on the same site as the Norman Church.

There are currently four churches in Upton:

• St Mary's Church, the Church of England Parish Church in Ford Road
• St Joseph's Church, the Roman Catholic Parish Church in Moreton Road
• The United Reformed Church in Ford Road
• The Jubilee Church which meets in Overchurch Primary School on Moreton Road