The house remained empty until the shipping owner, Ralph Leyland, bought it in 1884.

About 1893 Mr Leyland moved to Liverpool due to financial problems, and the house was let to Colonel Robinson for three years.

Following Colonel Robinson's departure, the house was again empty for four years, until 1902 when Ralph Leyland returned.

Mr Leyland remained in the house untill 1910 when he sold it to Mr Stern. During the time he owned the house, Mr Leyland sold off most of the extensive land to pay his debts.

Shortly after buying the house, Mr Stern further extended it. Mr Stern lived at the Manor house until his death in 1950.

In 1951 the FCJ sisters (from Upton Hall) bought the house and it was used first to provide additional boarding space and then, from 1959, it housed the junior school. For more information on Upton Manor during the time it was owned by the FCJ sisters, see the entry in the Schools section.

In 1984, due to the cost of upkeep of the building, the sisters closed the junior school and the house once again was empty for the next three years.

In 1987 McCarthy Stone bought the house and converted it into a nursing home, they added a new wing to the building and built sheltered housing in the grounds. The building was renamed 'The Manor House'.

In March 1974 Upton Manor was given Grade II listed status, the official description, taken from 'The Buildings of England - Cheshire' by N Pevsner and E Hubbard, is as follows:

“… House, now in use as nursing home. c1857. Probably by John Cunningham. Ashlar with Welsh slate roof. 2 storeys, 4 window range, with later taller rear block with attic storey. Central entrance in porch with paired Doric columns, flanking sash windows and full height bay window. 3 window return elevation with central full height canted bay. Windows throughout in stressed architraves with pedimented hoodsto ground floor. Modillion cornice to eaves, angle quoins. Rear block added later but in similar style. 5 window range to garden front, with outer canted bay windows to ground floor with balustraded parapets. 16 pane sash windows above. Ground floor windows have pedimented hoods, and all are in stressed architraves. Attic storey with segmentally arched dormers breaking the eaves line. Belvedere tower with triple round arched windows and low pyramidal door to rear. Axial stacks. ….”